My Dear Readers! When I was asked to talk about mental health, specifically autistic spectrum disorder and attention hyperactivity syndrome and oxidative stress, at the event to support “Smiles Non-profit shop society”, I was indeed … Read more
On a day of “physical challenges”, Amanda Bucklaschuk and yours truly were conversing on gratitude of little achievements and personal celebrations, a token of self-love.
I am sure you know that I love to learn and teach, thus every morning starts with reviewing papers. And I love when medical/research papers enforce or validate or support and strengthen my knowledge. Being … Read more
Whether it is with your food choices, or adding regular daily exercise or indeed, adding NAD protandim. Upon latest reading, and finding some very “impressive” slides, I would really love to share that information with you. Also … Read more
My dear readers! I would like to introduce you to the concept of personalized nutrition in accordance to your genetic profile. I am learning this from Dr. Jeffery Bland, MD, PhD and “father” of functional … Read more
This month I am featured in this month’s issue of the Alberta Cancer Foundation magazine …. “My legacy is in teaching people health,” says Silverman. “If I managed to teach them to change their lifestyle, … Read more
We are very sorry about the recent posts, they were not made by us. We have fixed the issue and you will no longer be seeing strange posts. Please, stay tuned for new posts coming … Read more
As you all know, I am a true advocate and totally “crazy” about NRF2 protein complex in health and disease. However, I keep learning more and more about “another” guy: NRF1. It turns out that properly up-regulated NRF1 is also critically important for our well-being. We know that NRF1 is a protein complex, activating genes, responsible for mitochondrial biogenesis (production of new mitochondria).
NRF1 is a whole more than just our mitochondrial booster:
- “It is now widely recognized that NRF1 is a multifunctional protein with critical roles in diverse cellular functions…”
- “NRF1 binds to ~691 genes encoding proteins regulating cellular growth, DNA replication, DNA repair, chromosome organization and mRNA processing. NRF1 binds to promoter sequences of thousands of genes involved in regulating RNA metabolism, DNA damage repair, protein translation, cell cycle progression and more…”
- “NRF1 has also been found to regulate human telomere transcription..”
- “NRF1 protects neural stem cells from neurotoxin-induced apoptosis and senescence-aka dementia”..
Bottom line: NRF1 protein complex needs and MUST be upregulated in a healthy manner.
Reference: Cellular Oncology, October 2018
Interplay between NRF1, E2F4 and MYC transcription factors regulating common target genes contributes to cancer development and progression
Kaumudi Bhawe & Deodutta Roy
As I was catching up on my emails emails and reading scientific conventional medical and alternative medicine journals, I was delighted to come across this paper: Quantifying the effects of spirulina supplementation on plasma lipid … Read more
Please forgive me for not writing for so long. And it’s not that there is nothing to talk or share or teach, on contrary, there is plenty. My desire to share, teach, explain is … Read more