NRF2 Activation

My dearest friends and readers and followers! 

It is my deepest pleasure to introduce a second episode of my 5 parts mini-series on health and wellness. It is all about NRF2 activation. 

...”The Nrf2 signalling pathway is emerging as a critical and principal factor in the protection against cancer, neurodegeneration, and inflammation (Hayes and McMahon 2001; Droge and Schipper 2007; Nair et al.2007)…

Your health resides on cellular cleanliness and NRF2, cellular health guardian, is responsible for turning on “cellular vacuum cleaners” switch.

I would love to quote my NRF2 mentor and discoverer of NRF2-Keap1 regulatory complex Dr. M. Yamamoto, MD, PhD: 

…”Cellular detoxification is essential for health because it provides protection against various chemicals and xenobiotics. The KEAP1-NRF2system is important for cellular defense against oxidative and electrophilic stresses as NRF2 activates the transcription of an array of cytoprotective genes, including drug-metabolizing and antioxidant enzymes, in a stress-dependent manner…”

Please enjoy this presentation on health and I am so looking forward to your feedback, and questions. 

From my heart to yours, 

With love, Dr. Sveta Silverman, MD